Statins for Acute Ischemic Stroke
نویسندگان
چکیده
منابع مشابه
Statins for acute ischemic stroke.
BACKGROUND Statins have been claimed to be effective in the acute phase of ischemic stroke. The potential positive actions of statins during an acute cerebrovascular ischemic event are two-fold: a neuroprotective effect, limiting damage and improving recovery; and a preventative effect on early recurrence. OBJECTIVES To quantify the potential benefits and harms of statins in the acute treatme...
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BACKGROUND AND PURPOSE Statins have pleiotropic effects of potential neuroprotection. However, because of lack of large randomized clinical trials, current guidelines do not provide specific recommendations on statin initiation in acute ischemic stroke (AIS). The current study aims to systematically review the statin effect in AIS. METHODS From literature review, we identified articles explor...
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Ischemic stroke has been classified as a merely thrombotic disease, so the main goal of its treatment is the recanalization of the occluded vasculature. However, despite fast restoration of blood circulation, progressive stroke still develops in many patients, which has led to the concept of reperfusion injury. The underlying mechanism is only partly known. Though, it is accepted now, tha...
متن کاملGangliosides for acute ischemic stroke.
BACKGROUND Gangliosides may have a protective effect on the central and peripheral nervous systems. OBJECTIVES The objective of this review was to assess the effect of exogenous gangliosides in acute ischaemic stroke. SEARCH STRATEGY We searched the Cochrane Stroke Group trials register (last searched: May 2001) and contacted drug companies and main investigators of included trials. SELEC...
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ژورنال
عنوان ژورنال: Stroke
سال: 2012
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.111.638940